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Grand RoundsWeekly Evidence Brief

Transplant Surgery

Edition

30-Second Takeaway

  • Prehabilitation shortens hospital stay and improves 6‑minute walk distance in transplant candidates.
  • EHR‑integrated AI risk prediction, when passively available, did not improve SDM or communication.

Week ending May 16, 2026

Grand Rounds: Selected transplant-surgery evidence briefs

EHR‑integrated AI risk prediction did not change SDM or outcomes in kidney transplant recipients

NPJ DIGITAL MEDICINEMay 15, 2026

In a single‑center randomized trial (n=76, eGFR<30) EHR‑available AI risk estimates did not increase patient‑reported conversations about post‑graft‑loss options (14/36 vs 16/40). No differences were seen in secondary SDM, relationship, or distress measures across 12 months. Tool uptake was low and users reported workflow barriers, suggesting implementation failure rather than model ineffectiveness.

Instrumental‑variable analysis removes apparent MAG survival benefit after CABG in older Medicare patients

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGYMay 13, 2026

In 1,291,314 Medicare CABG patients, conventional risk‑adjusted analysis showed MAG median survival 10.74 vs 10.33 years for SAG. Using surgeon MAG rate as an instrumental variable, adjusted median survival was identical: 10.38 years for both groups. This contrast implies unmeasured confounding likely explains much of the observational MAG survival advantage.

Robot‑assisted kidney transplantation reduced early major and vascular complications numerically

EUROPEAN UROLOGYMay 10, 2026

In this randomized open‑label trial (robot n=54, open n=53) major surgical complications occurred in 13 (25%) open vs 7 (13%) robotic patients (risk difference −11%). Vascular complications were 19% open vs 9.4% robotic (risk difference −9.4%). Findings suggest possible short‑term morbidity reduction with robotic KTx but are limited by single‑centre design and modest sample size, and results were not statistically definitive.

References

Numbered in order of appearance. Click any reference to view details.

Additional Reads

Optional additional studies from this edition.

Edition context

Clinical signal

  • Interpret observational MAG survival benefits cautiously; IV analyses may remove apparent advantage.
  • Consider robotic kidney transplantation to reduce early surgical complications, but note limited sample size and single‑centre data.
  • When implementing prehabilitation, monitor adherence and exercise dose; evidence certainty is variable.