Grand Rounds

Gastroenterology weekly journal

Care for the digestive system and its disorders, from the esophagus to the rectum.

Latest issue

Jul 4, 2026

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GastroenterologyLatest first

2026

Jul 4

2026

Grand Rounds issue

Selected recent evidence for GI practice: immersive VR for cancer symptoms, RWE methods for GLP‑1 therapies, Zelen trial acceptability, and a fermented brown rice product for constipation

Effects of Immersive Virtual Reality Interventions on Symptom Management in Patients With Gastrointestinal Cancer: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Methodological Approaches to Real-World Evidence Generation for Glucagon-like Peptide-1-Based Therapies: Synopsis of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop.

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Jun 27

2026

Grand Rounds issue

Concise evidence briefs for gastroenterologists: pediatric IBD therapies, DGBI clinician-patient methods, MTT delivery, IV iron safety in GI cancer, and gastric hyperplastic polyp malignancy risk

Benefit-risk balance of advanced therapies in pediatric inflammatory bowel disease: evidence and gaps versus adults.Methods to build and maintain effective clinician-patient relationships for adults with disorders of gut-brain interaction (DGBI): a systematic review.

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Jun 20

2026

Grand Rounds issue

MedBrevia Grand Rounds: Selected recent GI evidence brief

Advanced phenotypes and favorable 1-year outcomes with accelerated step-up strategy in newly diagnosed inflammatory bowel disease in a tuberculosis-endemic, resource-constrained setting.Efficacy and Safety of Probiotics, Prebiotics, and Synbiotics: An Umbrella Review of Systematic Reviews and Meta-Analysis of Randomized Controlled Trials.

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Jun 13

2026

Grand Rounds issue

MedBrevia Grand Rounds: Select GI Evidence Briefs

Clinical significance of isolated periappendiceal red patch in ulcerative colitis: A systematic review, meta-analysis, and meta-regression.The impact of normalization of histology on disease course in microscopic colitis: a retrospective cohort study.

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Jun 6

2026

Grand Rounds issue

Selected recent evidence affecting IBD, MASH, oncology supportive care, and patient-reported outcomes

Understanding Patient and Gastroenterologist Preferences at the Time of Treatment Escalation to First-Line Advanced Therapy in Ulcerative Colitis: A Discrete Choice Experiment in Five European Countries.Gut Microbiome Dysbiosis and Cancer: A Systematic Review on the Emerging Role of Probiotics in Oncology.

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May 30

2026

Grand Rounds issue

Grand Rounds: Selected recent advances in IBD, microbiome interventions, PBC endpoints, exercise-microbiota, and acute pancreatitis guidelines

Impact of advanced therapy initiation on antibiotic dependence in chronic pouchitis.Gut Microbiota Changes Following Aerobic Exercise in Malnourished Octogenarians: An Assessor-Blinded Intervention Study Stratified by Nutritional Status.

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May 23

2026

Grand Rounds issue

Five recent papers: sorafenib GI toxicity, FMT in sepsis and IBS, SDoH in GI cancer, and bias in 'personalized' RCTs

Prevalence of gastrointestinal side effects in hepatocellular carcinoma patients receiving sorafenib: a meta-analysis of 136 studies and 14,416 patients.Effects of fecal microbiota transplantation and probiotics on the gut microbiome in antibiotic-treated septic patients: A pilot randomized controlled trial.

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May 16

2026

Grand Rounds issue

Microbiome, diet, and digital supports in GI care: practical updates for clinicians

AGA Clinical Practice Update on Management of Clostridioides difficile Infection in Inflammatory Bowel Disease: Expert Review.Artificial Intelligence-Guided Personalized Gut Microbiome Modulation for Persistent Secondary Gastrointestinal Symptoms in Oncology Patients: Clinical Efficacy and Biological Correlates from a Prospective Validation Study.

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May 9

2026

Grand Rounds issue

Practical evidence briefs: IBD with IBS‑like symptoms, digital therapies, AI governance, and GI pathology models

Recommendations for the Evaluation and Management of Inflammatory Bowel Disease with Irritable Bowel Syndrome-Like Symptoms: A Joint Rome Foundation and International Organization for the Study of IBD (IOIBD) Consensus.Responsible use of large language models in gastroenterology and hepatology.

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May 2

2026

Grand Rounds issue

Selected recent evidence relevant to IBD, DGBI trials, metabolomics, pharmacology, and automated anesthesia for endoscopy

Design of Treatment Trials for Disorders of Gut-Brain Interaction.Recommendations for the Evaluation and Management of Inflammatory Bowel Disease with Irritable Bowel Syndrome-Like Symptoms: A Joint Rome Foundation and International Organization for the Study of IBD (IOIBD) Consensus.

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